Publikationen

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1. Knuever J, Poeggeler B, Gáspár E, Klinger M, Hellwig-Burgel T, Hardenbicker C, Tóth BI, Bíró T, Paus R.
   Thyrotropin-releasing hormone controls mitochondrial biology in human epidermis.
   J Clin Endocrinol Metab. 2012 Mar; 97(3):978-86.
   
   
   
2. Roth A, König P, van Zandbergen G, Klinger M, Hellwig-Bürgel T, Däubener W, Bohlmann MK, Rupp J.
   Hypoxia abrogates antichlamydial properties of IFN-γ in human fallopian tube cells in vitro and ex vivo.
   Proc Natl Acad Sci U S A. 2010 Nov 9; 107(45):19502-7.
   
   
   
3. Spanholtz T, Maichle A, Niedworok C, Stoeckelhuber BM, Krüger S, Wedel T, Aach T, Middeler G, Hellwig-Bürgel T, Bader A, Krengel S, Müller OJ, Franz WM, Lindenmaier W, Machens HG.
   Timing and targeting of cell-based VEGF165 gene expression in ischemic tissue.
   J Surg Res. 2009 Jan; 151(1):153-62.
   
   
   
4. Wagner AE, Huck G, Stiehl DP, Jelkmann W, Hellwig-Bürgel T.
   Dexamethasone impairs hypoxia-inducible factor-1 function.
   Biochem Biophys Res Commun. 2008 Jul 25;372(2):336-40.
   
   
   
5. Rupp J, Gieffers J, Klinger M, van Zandbergen G, Wrase R, Maass M, Solbach W, Deiwick J, Hellwig-Burgel T.
   Chlamydia pneumoniae directly interferes with HIF-1alpha stabilization in human host cells.
   Cell Microbiol. 2007 Sep;9(9):2181-91. Epub 2007 May 8.
   
   
   
6. Krajewski J, Batmunkh C, Jelkmann W, Hellwig-Bürgel T.
   Interleukin-1beta inhibits the hypoxic inducibility of the erythropoietin enhancer by suppressing hepatocyte nuclear factor-4alpha.
   Cell Mol Life Sci. 2007 Apr; 64(7-8):989-98.
   
   
   
7. Batmunkh C, Krajewski J, Jelkmann W, Hellwig-Bürgel T.
   Erythropoietin production: Molecular mechanisms of the antagonistic actions of cyclic adenosine monophosphate and interleukin-1.
   FEBS Lett. 2006 May 29; 580(13):3153-60. Epub 2006 May 2.
   
   
   
8. Hellwig-Bürgel T, Stiehl DP, Katschinski DM, Marxsen J, Kreft B, Jelkmann W.
   VEGF production by primary human renal proximal tubular cells: requirement of HIF-1, PI3-kinase and MAPKK-1 signaling.
   Cell Physiol Biochem. 2005;15(1-4):99-108.
   
   
   
9. Hellwig-Bürgel T, Stiehl DP, Wagner AE, Metzen E, Jelkmann W.
   Hypoxia-inducible factor-1 (HIF-1): a novel transcription factor in immune reactions.
   J Interferon Cytokine Res. 2005 Jun; 25(6):297-310. Review.
   
   
   
10. Metzen E, Stiehl DP, Doege K, Marxsen JH, Hellwig-Bürgel T, Jelkmann W.
    Regulation of the prolyl hydroxylase domain protein 2 (phd2/egln-1) gene: identification of a functional hypoxia-responsive element.
    Biochem J. 2005 May 1; 387(Pt 3):711-7.
    
    
    
11. Rupp J, Hellwig-Burgel T, Wobbe V, Seitzer U, Brandt E, Maass M.
    Chlamydia pneumoniae infection promotes a proliferative phenotype in the vasculature through Egr-1 activation in vitro and in vivo.
    Proc Natl Acad Sci U S A. 2005 Mar 1; 102(9):3447-52. Epub 2005 Feb 18.
    
    
    
12. Dendorfer A, Heidbreder M, Hellwig-Bürgel T, Jöhren O, Qadri F, Dominiak P.
    Deferoxamine induces prolonged cardiac preconditioning via accumulation of oxygen radicals.
    Free Radic Biol Med. 2005 Jan 1; 38(1):117-24.
    
    
    
13. Metzen E, Berchner-Pfannschmidt U, Stengel P, Marxsen JH, Stolze I, Klinger M, Huang WQ, Wotzlaw C, Hellwig-Bürgel T, Jelkmann W, Acker H, Fandrey J.
    Intracellular localisation of human HIF-1 alpha hydroxylases: implications for oxygen sensing.
    J Cell Sci. 2003 Apr 1;116(Pt 7):1319-26.
    
    
    
14. La Ferla K, Reimann C, Jelkmann W, Hellwig-Bürgel T.
    Inhibition of erythropoietin gene expression signaling involves the transcription factors GATA-2 and NF-kappaB.
    FASEB J. 2002 Nov;16(13):1811-3. Epub 2002 Sep 5.
    
    
    
15. Schmitt O, Schubert C, Feyerabend T, Hellwig-Bürgel T, Weiss C, Kühnel W.
    Preferential topography of proteins regulating vascularization and apoptosis in a MX1 xenotransplant after treatment with hypoxia, hyperthermia, ifosfamide, and irradiation.
    Am J Clin Oncol. 2002 Aug;25(4):325-36.
    
    
    
16. Stiehl DP, Jelkmann W, Wenger RH, Hellwig-Bürgel T.
    Normoxic induction of the hypoxia-inducible factor 1alpha by insulin and interleukin-1beta involves the phosphatidylinositol 3-kinase pathway.
    FEBS Lett. 2002 Feb 13;512(1-3):157-62.
    
    
    
17. Jelkmann W, Hellwig-Bürgel T.
    Biology of erythropoietin.
    Adv Exp Med Biol. 2001;502:169-87. Review.
    
    
    
18. Marxsen JH, Schmitt O, Metzen E, Jelkmann W, Hellwig-Bürgel T.
    Vascular endothelial growth factor gene expression in the human breast cancer cell line MX-1 is controlled by O2 availability in vitro and in vivo.
    Ann Anat. 2001 May;183(3):243-9.
    
    
    
19. El Awad B, Kreft B, Wolber EM, Hellwig-Bürgel T, Metzen E, Fandrey J, Jelkmann W.
    Hypoxia and interleukin-1beta stimulate vascular endothelial growth factor production in human proximal tubular cells.
    Kidney Int. 2000 Jul; 58(1):43-50.
    
    
    
20. Kunze B, Hellwig-Bürgel T, Weichenhan D, Traut W.
    Transcription and proper splicing of a mammalian gene in yeast.
    Gene. 2000 Apr 4; 246(1-2):93-102.
    
    
    
21. Hellwig-Bürgel T, Rutkowski K, Metzen E, Fandrey J, Jelkmann W.
    Interleukin-1beta and tumor necrosis factor-alpha stimulate DNA binding of hypoxia-inducible factor-1.
    Blood. 1999 Sep 1; 94(5):1561-7.
    
    
    
22. Jelkmann W, Hellwig-Buergel T.
    Tumor necrosis factor p55 receptor (TNF-RI) mediates the in vitro inhibition of hepatic erythropoietin production.
    Exp Hematol. 1999 Feb;27(2):224-8.
    
    
    
23. Frede S, Fandrey J, Pagel H, Hellwig T, Jelkmann W.
    Erythropoietin gene expression is suppressed after lipopolysaccharide or interleukin-1 beta injections in rats.
    Am J Physiol. 1997 Sep; 273(3 Pt 2):R1067-71.
    
    
    
24. Jelkmann W, Pagel H, Hellwig T, Fandrey J.
    Effects of antioxidant vitamins on renal and hepatic erythropoietin production.
    Kidney Int. 1997 Feb; 51(2):497-501.
    
    
    
25. Plass C, Weichenhan D, Kunze B, Hellwig T, Schneider C, Bautz FA, Grzeschik KH, Traut W, Winking H.
    A member of the mouse LRR transcript family with homology to the human Sp100 gene.
    Hereditas. 1995; 122(3):245-56.
    
    
    
26. Weichenhan D, Kunze B, Plass C, Hellwig T, Winking H, Traut W.
    A transcript family from a long-range repeat cluster of the house mouse.
    Genome. 1995 Apr; 38(2):239-45.
    
    
    
27. Plass C, Hellwig T, Traut W, Winking H.
    Evolution of a B2 tagged sequence from a long-range repeat family in the genus Mus.
    Mamm Genome. 1992;3(4):197-201.
    

 

Buchbeiträge

Hellwig-Bürgel T, Stiehl DP, Jelkmann W.
Hypoxia-Inducible Factor-1. More than a hypoxia-inducible transcription factor.
In: Oxygen Sensing. Responses and Aaptation to Hypoxia.
Lahiri S, Semenza GL, Prabhakar NR. (Eds.)
Marcel Decker, Inc. New York - Basel. 2003:95-108.

Beiträge auf Deutsch

Kunze B, Hellwig-Bürgel T.
Ssaccharomyces cerevisiae ein molekularbiologisches Universalgenie?
BIOforum. 11/2001:835-36.

Hellwig-Bürgel T, La Ferla-Brühl K, Reimann C, Krajewski J, Jelkmann W.
Die Balance der Transkriptionsfaktoren: Entschlüsselung der molekularen Ursache der Anämie chronischer Entzündungen.
Focus MUL. 2002 Dec(4):216-20.