Publikationen 1999-2024

 

 

  1. Theodoraki MN, Huber D, Hofmann L, Werner L, Idel C, Fleckner J, Plötze-Martin K, Schütt L, Brunner C, Depping R, Hoffmann TK, Bruchhage KL, Pries R
    Type 2-like polarization and elevated CXCL4 secretion of monocyte derived macrophages upon internalization of plasma-derived exosomes from head and neck cancer patients
    BMC Cancer. 2024 Sep 20;24(1):1173. doi: 10.1186/s12885-024-12948-6

  2. Rother F, Depping R, Popova E, Huegel S, Heiler A, Hartmann E, Bader M
    Karyopherin α2 is a maternal effect gene required for early embryonic development and female fertility in mice
    FASEB J. 2024 Apr 30;38(8):e23623. doi: 10.1096/fj.202301572RR

  3. Ralph Pries, Friederike Katharina Kosyna, Reinhard Depping, Kirstin Plötze-Martin, Christian Lange, Svenja Meyhöfer, Sebastian M. Meyhöfer, Jens U. Marquardt, Karl-Ludwig Bruchhage & Armin Steffen
    Distinguishing the impact of distinct obstructive sleep apnea syndrome (OSAS) and obesity related factors on human monocyte subsets
    Scientific Reports volume 14, Article number: 340 (2024)

  4. Hoffmeister H, Holzinger S, Dürr MS, Bruckmann A, Schindler S, Gröbner-Ferreira R, Depping R, Längst G
    Characterization of the nuclear import of human CHD4-NuRD complex
    J Cell Sci. 2023 Mar 2:jcs.260724. doi: 10.1242/jcs.260724. Online ahead of print. PMID: 36861403

  5. Ozkurt M, Hellwig-Bürgel T, Depping R, Kadabere S, Ozyurt R, Karadag A, Erkasap N
    miR663 Prevents Epo Inhibition Caused by TNF-Alpha in Normoxia and Hypoxia
    Int J Endocrinol 2021 Jul 27; 2021:3670499. doi: 10.1155/2021/3670499.eCollection

  6. von Fallois M, Kosyna FK, Mandl M, Landesman Y, Dunst J, Depping R
    Selinexor decreases HIF-1α via inhibition of CRM1 in human osteosarcoma and hepatoma cells associated with an increased radiosensitivity
    J Cancer Res Clin Oncol 2021 Apr 15 doi: 10.1007/s00432-021-03626-2. Online ahead of print.

  7. Post H, Hundt JE, Zhang G, Depping R, Rose C, Langan EA, Paus R
    Thyroxine Restores Severely Impaired Cutaneous Re-Epithelialisation and Angiogenesis in a Novel Preclinical Assay for Studying Human Skin Wound Healing Under "Pathological" Conditions Ex Vivo
    Arch Dermatol Res 2020 Jun 22. doi: 10.1007/s00403-020-02092-z. Online ahead of print

  8. Depping R, von Fallois M, Landesman Y, Kosyna FK
    The Nuclear Export Inhibitor Selinexor Inhibits Hypoxia Signaling Pathways And 3D Spheroid Growth Of Cancer Cells.
    Onco Targets Ther. 2019 Oct 11;12:8387-8399. doi: 10.2147/OTT.S213208. eCollection 2019

  9. Depping R, Seeger K
    H-NMR spectroscopy shows cellular uptake of HEPES buffer by human cell lines-an effect to be considered in cell culture experiments
    Anal Bioanal Chem. 2019 Feb;411(4):797-802

     

  10. Kosyna FK, Depping R
    Controlling the Gatekeeper: Therapeutic Targeting of Nuclear Transport
    Cells 2018 Nov 21;7(11). pii:E221 doi: 3390/cells7110221. Review.
  11. Tazat K, Schindler S, Depping R, Mabjeesh NJ
    Septin 9 isoform 1 (SEPT9_i1) specifically interacts with importin-α7 to drive hypoxia-inducible factor (HIF)-1α nuclear translocation.
    Cytoskeleton (Hoboken). 2018 May 9. doi: 10.1002/cm.21450. [Epub ahead of print]

     
  12. Ménard M, Costechareyre C, Ichim G, Blachier J, Neves D, Jarrosson-Wuilleme L, Depping R, Koster J, Saintigny P, Mehlen P, Tauszig-Delamasure S
    Hey1- and p53-dependent TrkC proapoptotic activity controls neuroblastoma growth
    PLoS Biol. 2018 May 11;16(5):e2002912. doi: 10.1371/journal.pbio.2002912. [Epub ahead of print]

     

     

  13. Sowa AS, Martin E, Martins IM, Schmidt J, Depping R, Weber JJ, Rother F, Hartmann E, Bader M, Riess O, Tricoire H, Schmidt T
    Karyopherin α-3 is a key protein in the pathogenesis of spinocerebellar ataxia type 3 controlling the nuclear localization of ataxin-3
    Proc Natl Acad Sci U S A: 115(11):E2624-E2633, Epub 2018

     

     

  14. Depping R, Oster H
    Interplay between environmentally modulated feedback loops - hypoxia and circadian rhythms - two sides of the same coin?
    FEBS J, 284(22):3801-3803, 2017

     

     

  15. Mandl M, Depping R 

    ARNT is a potential direct HIF-1 target gene in human Hep3B hepatocellular carcinoma cells

    Cancer Cell Int 17:77 doi: 10.1186/s 12935-017-0446-2, 2017

     

     

  16. Richter A, Hollstein R, Hebert E, Vulinovic F, Eckhold J, Osmanovic A, Depping R, Kaiser FJ, Lohmann K

    In-depth Characterization of the Homodimerization Domain of the Transcription Factor THAP1 and Dystonia-Causing Mutations Therein

    J Mol Neurosci 10.1007/s 12031-017-0904-2, 2017 [Epub ahead of print]

     

  17. Wolff M, Kosyna FK, Dunst J, Jelkmann W, Depping R

    Impact of hypoxia inducible factors on estrogen receptor expression in breast cancer cells

    Arch Biochem Biophys S0003-9861(16)30457-X, 2017

  18. von Fallois M, Depping R
    Radiation response enhanced by inhibition of XPO1 in preclinical rectal cancer models
    Strahlenther Onkol 2016 [Epub ahead of print]
  19. Baumann R, Depping R, Delaperrier M, Dunst J
    Targeting hypoxia to overcome radiation resistance in head & neck cancers: real challenge or clinical fairytale?Expert Rev Anticancer Ther 2016 [Epub ahead of print]

     

  20. Mandl M, Lieberunm M, Dunst J, Depping R

    The expression level of the transcription factor Aryl hydrocarbon receptor nuclear translocator (ARNT) determines cellular survival after radiation treatment

    Radiat Oncol 10: 229

     

     

  21. Sun W, Kosyna FK, Jelkmann W, Depping R

    Prolyl-4-Hydroxylase 2 Potentially Contributes to Hepatocellular Carcinoma-Associated Erythrocytosis ba Maintaining Hepatocyte Nuclear-4alpha Expression

    Cell Physiol Biochem 37(6): 2257-64, 2015

     

     

     

  22. Kosyna FK, Nagel M, Kluxen L, Kraushaar K, Depping R

    The importin α/β-specific inhibitor Ivermectin affects HIF-dependent hypoxia response pathways

    Biol Chem pii: /j/bchm.ahead-of-print/hsz-2015-0171/hsz-2015-0171.xml [Epub ahead of print]

     

     

  23. Gemoll T, Epping F, Heinrich L, Fritzsche B, Roblick UJ, Szymczak S, Hartwig S, Depping R, Bruch, HP, Thorns C, Lehr S, Paech A, Habermann JK 

    Increased cathepsin D protein expression is a biomarker for osteosarcomas, pulmonary metastases and other bone malignancies

    Oncotarget 6(18): 16517-26, 2015

     

     

  24. Schraivogel D, Schindler SG, Danner J, Kremmer E, Pfaff J, Hannus S, Depping R, Meister G 

    Importin-beta facilitates nuclear import of human GW proteins and balances cytoplasmic gene silencing protein levels

    Nucleic Acids Res. 2015 Jul 13. pii: gkv705. [Epub ahead of print]

     

     

  25. Depping R, Jelkmann W, Kosyna FK
    Nuclear-cytoplasmatic shuttling of proteins in control of cellular oxygen sensing

    J Mol Med (Berl) [Epub ahead of print], 2015

     

  26.  

    Erogullari A, Hollstein R, Seibler P, Braunholz D, Koschmidder E, Depping R, Eckhold J, Lohnau T, Gillessen-Kaesbach G, Grünewald A, Rakovic A, Lohmann K, Kaiser FJ

    THAP1, the gene mutated in DYT6 dystonia, autoregulates its own expression

    Biochim Biophys Acta. 2014 Aug 1. pii: S1874-9399(14)00207-7. doi: 10.1016/j.bbagrm.2014.07.019. [Epub ahead of print]

     

  27. Huegel, S, Depping R, Dittmar G, Rother F, Cabot R, Sury MD, Hartmann E, Bader M

    Identification of importin alpha 7 specific transport cargoes using a proteomic screening approach

    Mol Cell Proteomics, [Epub ahead of print], 2014

     

     

     

     

  28. Sun W, Depping R, Jelkmann W

    Interleukin-1β promotes hypoxia-induced apoptosis of
    glioblastoma cells by inhibiting hypoxia-inducible
    factor-1 mediated adrenomedullin production

    Cell Death and Disease 5, e1020; doi:10.1038/cddis.2013.562, 2014

     

     

     

     

     

  29. Sun W, Jelkmann W, Depping R

    Prolyl-4-hydroxylase 2 enhances hypoxia-induced glioblastoma cell death by regulating the gene expression of hypoxia-inducible factor-?

    Cell Death Dis. 2014 Jul 10;5:e1322. doi: 10.1038/cddis.2014.295

     

  30. Mandl M, Depping R

    Hypoxia-inducible ARNT (HIF-1β): a rare exception?

    Mol Med 10.2119/molmed.2014.00032 [Epub ahead of print]

     

  31. Mallavia B, Recio C, Oguiza A, Ortiz-Muñoz G, Lazaro I, Lopez-Parra V, Lopez-Franco O, Schindler S, Depping R, Egido J, Gomez-Guerrero C.
    Peptide Inhibitor of Nuclear Factor-κB Translocation Ameliorates Experimental Atherosclerosis
    Am J Pathol. 2013 Apr 5.
  32. Wolff M, Jelkmann W, Dunst J, Depping R
    The aryl hydrocarbon receptor nuclear translocator (ARNT/HIF-1ß) is influenced by hypoxia and hypoxia-mimetics.
    Cell Physiol Biochem 32(4):849-858 [Epub ahead of print], 2013

  33. Pientka FK, Hu J, Schindler SG, Brix B, Thiel A, Jöhren O, Fandrey J, Berchner-Pfannschmidt U, Depping R.
    Oxygen sensing by the prolyl-4-hydroxylase PHD2 within the nuclear compartment and the influence of compartmentalisation on HIF-1 signalling.
    J Cell Sci. 2012 Nov 1;125(Pt 21):5168-7

  34. von Brandenstein, M., Schlosser, M., Richter, C., Depping, R., Fries, JW.
    ETS-dependent p16(INK4a) and p21(waf1/cip1) gene expression upon endothelin-1 stimulation in malignant versus and non-malignant proximal tubule cells.
    Life Sci. 2012 Apr 12. [Epub ahead of print]

  35. Depping, R., Schindler, S.G., Jacobi, C., Kirschner, k.M., Scholz, H.
    Nuclear transport of Wilms´tumor protein Wt1 involves importins alpha and beta
    Cell Physiol Biochem. 2012;29(1-2):223-32

  36. Ströfer, M., Jelkmann, W., Metzen, E., Brockmeier, U., Dunst, J.,
    Depping, R.
    Stabilisation and knockdown of HIF - two distinct ways comparably important in radiotherapy.
    Cell Physiol Biochem. 2011;28(5):805-12.

  37. Ströfer M, Jelkmann W, Depping R.
    Curcumin decreases survival of Hep3B liver and MCF-7 breast cancer cells: the role of HIF.
    Strahlenther Onkol. 2011 Jul;187(7):393-400. Epub 2011 Jun 27.

  38. von Brandenstein M, Depping R, Schäfer E, Dienes HP, Fries JW.
    Protein kinase C α regulates nuclear pri-microRNA 15a release as part of endothelin signaling.
    Biochim Biophys Acta. 2011 Oct;1813(10):1793-802. Epub 2011 Jun 21.

  39. Martrat G, Maxwell CA, Tominaga E, Porta M, Bonifaci N, Gomez-Baldo L, Bogliolo M, Lazaro C, Blanco I, Brunet J, Aguilar H, Fernandez-Rodriguez J, Seal S, Renwick A, Rahman N, Kuhl J, Neveling K, Schindler D, Ramirez MJ, Castella M, Hernandez G, Embrace ES, Easton DF, Peock S, Cook M, Oliver CT, Frost D, Platte R, Evans DG, Lalloo F, Eeles R, Izatt L, Chu C, Davidson R, Ong KR, Cook J, Douglas F, Hodgson S, Brewer C, Morrison PJ, Porteous M, Peterlongo P, Manoukian S, Peissel B, Zaffaroni D, Roversi G, Barile M, Viel A, Pasini B, Ottini L, Putignano AL, Savarese A, Bernard L, Radice P, Healey S, Spurdle A, Chen X, Beesley J, Kconfab KC, Rookus MA, Verhoef S, Tilanus-Linthorst MA, Vreeswijk MP, Asperen CJ, Bodmer D, Ausems MG, van Os TA, Blok MJ, Meijers-Heijboer HE, Hogervorst FB, Hebon HB, Goldgar DE, Buys S, John EM, Miron A, Southey M, Daly MB, Bcfr BC, Swe-Brca SB, Harbst K, Borg A, Rantala J, Barbany-Bustinza G, Ehrencrona H, Stenmark-Askmalm M, Kaufman B, Laitman Y, Milgrom R, Friedman E, Domchek SM, Nathanson KL, Rebbeck TR, Johannsson OT, Couch FJ, Wang X, Fredericksen Z, Cuadras D, Moreno V, Pientka FK, Depping R, Caldes T, Osorio A, Benitez J, Bueren J, Heikkinen T, Nevanlinna H, Hamann U, Torres D, Caligo MA, Godwin AK, Imyanitov EN, Janavicius R, Gemo GG, Sinilnikova OM, Stoppa-Lyonnet D, Mazoyer S, Verny-Pierre C, Castera L, de Pauw A, Bignon YJ, Uhrhammer N, Peyrat JP, Vennin P, Fert Ferrer S, Collonge-Rame MA, Mortemousque I, McGuffog L, Chenevix-Trench G, Pereira-Smith OM, Antoniou AC, Ceron J, Tominaga K, Surralles J, Pujana MA.
    Exploring the link between MORF4L1 and risk of breast cancer.
    Breast Cancer Res. 2011 Apr 5;13(2):R40. [Epub ahead of print]

  40. Ao Z, Jayappa KD, Wang B, Zheng Y, Kung S, Rassart E, Depping R,
    Kohler M, Cohen EA, Yao X.
    Importin α3 interacts with HIV-1 integrase and contributes to HIV-1 nuclear import and replication.
    J Virol. 2010 Sep;84(17):8650-63
     

  41. Huenniger K, Krämer A, Soom M, Chang I, Köhler M, Depping R, Kehlenbach RH, Kaether C.
    Notch1 signaling is mediated by importins alpha 3, 4, and 7.
    Cell Mol Life Sci. 2010 Sep;67(18):3187-96.
     

  42. Babin-Ebell J, Sievers HH, Charitos EI, Klein HM, Jung F, Hellberg AK, Depping R, Sier HA, Marxsen J, Stoelting S, Kraatz EG, Wagner KF
    Transmyocardial Laser Revascularization Combined with Intramyocardial Endothelial Progenitor Cell Transplantation in Patients with Intractable Ischemic Heart Disease Ineligible for Conventional Revascularization: Preliminary Results in a Highly Selected Small Patient Cohort
    Thorac Cardiov Surg 58:11-16, 2010
     

  43. Steinhoff A, Pientka FK, Möckel S, Kettelhake A, Hartmann E, Köhler M, Depping R.
    Cellular oxygen sensing: Importins and exportins are mediators of intracellular localisation of proly-4-hydroxylases PHD1 and PHD2 
    Biochem Biophys Res Commun. 2009 Oct 2;387(4):705-11.
     

  44. Wuelling M., Kaiser FJ, Buelens LA, Braunholz D., Shivdasani RA,
    Depping R., Vortkamp A. 
    Trps1, a regulator of chondrocyte proliferation and differentiation, interacts with the activator form of Gli3. 
    Dev Biol. 2009 Apr 1;328(1):40-53.
     

  45. von Brandenstein MG, Ngum Abety A, Depping, R, Roth, T, Koehler, M., Dienes, HP, Fries, JW
    A p38-p65 transcription complex induced by endothelin-1 mediates signal transduction in cancer cells. 
    Biochim Biophys Acta. 2008 Sep;1783(9):1613-22.

     
  46. Aherrahrou Z., Doehring LC., Maria-Ehlers, E., Liptau, H., Depping, R., Linsel-Nitschke, P., Kaczmarek, PM., Erdmann, J., Schunkert, H.
    An alternative splice variant in ABCC6, the gene causing dystrophic calcification, leads to protein deficiency in C3H/He mice.
    J Biol Chem. 2008 Mar 21;283(12):7608-15

     
  47. Depping R., Steinhoff, A., Schindler, S, Friedrich, B, Fagerlund, R.,
    Metzen, E, Hartmann, E., Köhler, M.
    Nuclear translocation of hypoxia-inducible factors (HIFs): Involvement of the classical importin a/b pathway.
    Biochim Biophys Acta. 2008 Mar;1783(3):394-404

     
  48. Laugsch M., Metzen E., Svensson T., Depping R., Jelkmann W.
    Lack of functional erythropoietin receptors of cancer cell lines.
    Int J Cancer. 2008 Mar 1;122(5):1005-11

     
  49. Bohm J., Kaiser F.J., Borozdin W., Depping R., Kohlhase J. 
    Synergistic cooperation of Sall4 and Cyclin D1 in transcriptional repression.
    Biochem Biophys Res Commun. 2007 May 11;356(3):773-9

     

  50. Heidbreder, M., Qadri, F., Jöhren, O., Dendorfer, A., Depping, R.;
    Fröhlich, R., Wagner, K.F., Dominiak, P.
    Non-hypoxic induction of HIF-3a by 2-deoxy-D-glucose and insulin
    Biochem Biophys Res Commun. 2007 Jan 12;352(2):437-43
     

  51. Depping, R., Kawakami K.,Ocker, H.,Wagner, JM.,Heringlake, M.,
    Noetzold, A., Sievers, HH., Wagner, KF.
    Expression of the Erythropoietin Receptor in Human Heart
    J. Thoracic and Carciovascular Surgery, 2005, Sep 130: 877-8
     

  52. Depping, R., Lohaus, C., Meyer, HE., Rüger, W. 
    The mono-ADP-ribosyltransferases Alt and ModB of bacteriophage T4: Target proteins identified
    Biochem Biophys Res Commun. 2005 Aug 18;  335(4):1217-23
     

  53. Tiemann, B., Depping, R., Kaliniene, L., Gineikiene, E., Nivinskas, R.,  Rüger, W.
    ModA and ModB, two ADP-Ribosyltransferases encoded by bacteriophage T4:Catalytic properties and mutation analysis
    Journal of Bacteriology, 2004, Nov 186 (21):7262-7272
     

  54. Sommer N, Depping R, Piotrowski M, Rüger W.
    Bacteriophage T4 alpha-glucosyltransferase: a novel interaction with  gp45 and aspects of the catalytic mechanism.
    Biochem Biophys Res Commun. 2004 Oct 22;323(3):809-815
     

  55. Wagner KF, Hellberg AK, Balenger S, Depping R, Dodd-O J, Johns RA, Li D.
    HIMF has anti-apoptotic action and is upregulated in developing lung: co-expression with HIF-2α.
    Am J Respir Cell Mol Biol. 2004 Sep;31(3):276-82
     

  56. Depping,R.,Hagele,S., Wagner, KF.,Wiesner, RJ.,Camenisch, G.,Wenger, RH., Katschinski,DM.
    A Dominant-Negative Isoform of Hypoxia-Inducible Factor-1a Specifically Expressed in Human Testis.
    Biol Reprod. 2004 Jul;71(1):331-9

  57. Hasegawa J, Wagner KF, Karp D, Li D, Shibata J, Heringlake M,
    Bahlmann L, Depping R, Fandrey J, Schmucker P, Uhlig S.
    Altered pulmonary vascular reactivity in mice with excessive erythrocytosis. 
    Am J Respir Crit Care Med. 2004 Apr 1;169(7):829-35
     

  58. Katschinski DM, Marti HH, Wagner KF, Shibata J, Eckhardt K, Martin F, Depping R, Paasch U, Gassmann M, Ledermann B, Desbaillets I,
    Wenger RH.
    Targeted disruption of the mouse PAS domain serine/threonine kinase PASKIN.
    Mol Cell Biol. 2003 Oct;23(19):6780-9
     

  59. Tiemann B, Depping R, Rüger W.
    Overexpression, purification, and partial characterization of ADP-ribosyltransferases modA and modB of bacteriophage T4.
    Gene Expr. 1999;8(3):187-96

 

Wir danken der DFG, der Forschungsförderung der medizinischen Fakultät der Universität zu Lübeck, dem DAAD, 
dem Bundesinstitut für Sportwissenschaft und der Erwin Riesch Stiftung für die Forschungsförderung.

Abstracts 1998-2013

  1. Sun W., Depping, R., Jelkmann, W.
    Influence of Interleukin-1b on the glucose metabolism in glioblastoma cells.
    92th Annual Meeting Congress of the DPG 2013, Heidelberg, 02-05.03.13

  2. Lohmann, K., Erogullari, A., Seibler, P., Braunholz, D., Grünewald, A., Depping, R., Eckhold, J., Albrecht, M., Rakovic, A., Lohnau, T.,
    Gillessen-Kaesbach, G., Klein, C.,  Kaiser, F.J.
    THAP1 expression in neurons derived from induced pluripotent stem cells: Evidence for autoregulation of THAP1.
    85. Kongress der Deutschen Gesellschaft für Neurologie, Hamburg, Germany, 26.-29.9.2012

  3. Sun, W., Hellwig-Bürgel, T., Depping, R., Jelkmann, W.
    Distinct impacts of interleukin-1beta on HIF-1a and HIF-2a in tumor cells.
    9th International Luebeck Conference on the "Pathophysiology and Pharmacology of Erythropoietin and other Hemopoietic Growth Factors, Lübeck, 13.-15.07.2012

  4. Erogullari, A., Seibler, P., Braunholz, D., Grünewald, A., Depping, R., Eckhold, J., Albrecht, M., Rakovic, A., Lohnau, T., Gillessen-Kaesbach, G., Klein, C., Lohmann, K., Kaiser, F.J.
    THAP1 activates the expression of SGCE (DYT11) and represses its own expression.
    16th International Congress of Parkinson's Disease and Movement Disorders, Dublin, Ireland, 17.-21.06.2012

  5. Depping, R., Schindler, S.G., Jacobi, C., Kirschner, K.M., Scholz, H.
    Nuclear transport of Wilms´tumor protein Wt1 involves importins a and b.
    91th Annual Meeting Congress of the DPG 2012, Dresden, 22-25.03.12

  6. Pientka, F.K., Hu, J., Schindler, S.G., Brix, B., Jöhren, O., Fandrey, J., Berchner-Pfannschmidt, U., Depping, R.
    Impact on HIF dependent oxygen sensing by regulation of the intracellular localization of PHD2.
    91th Annual Meeting Congress of the DPG 2012, Dresden, 22-25.03.12

  7. Pientka, F.K., Schindler, S.G., Brix, B., Depping, R.
    Enzymatic Activity of Prolyl-4-Hydroxylase PHD2 is predominantly effectvive in the nucleus.
    Molecular Life Sciences 2011, Frankfurt a.M., Germany, 25.-28.9.2011

  8. von Brandenstein, M., Depping, R., Schäfer, E., Dienes, H.-P., Fries, J.W.U.
    Protein kinase Ca regulates nuclear pri-microRNA 15a release as part of Endothelin signaling.
    The Twelfth International Conference on Endothelin, Cambridge, UK, 11.-14.September 2011

  9. Ströfer, M., Dunst, J., Depping, R., Jelkmann, W.
    Stabilizing and aboloshing hypoxia-inducible factor (HIF) - two distinct ways but comparable important in therapy.
    90th Annual Meeting Congress of the DPG 2011, Regensburg, 26-29.03.11
    Acta Physiologica, Vol. 201, Suppl. 682, March 2011

  10. Heidbreder, M., Jöhren, O., Depping, R., Vierke, G., Dendorfer, A.
    Regulation and transcriptional activities of four HIF-3a splice variants.
    90th Annual Meeting Congress of the DPG 2011, Regensburg, 26-29.03.11
    Acta Physiologica, Vol. 201, Suppl. 682, March 2011

  11. Pientka, F.K., Schindler, S.G., Brix, B., Hartmann, E., Depping, R.
    Impact of the intracellular localization of HIF prolyl hydroxylase 2 on the HIF pathway.
    90th Annual Meeting Congress of the DPG 2011, Regensburg, 26-29.03.11
    Acta Physiologica, Vol. 201, Suppl. 682, March 2011;Posterpreis

  12. Ströfer, M., Dunst, J., Jelkmann, W., Depping, R.
    Hypoxia and radiooncology - impact on radioresponsiveness of tumor cells.
    89th Annual Meeting Congress of the DPG 2010, Joint Meeting of the Scandinavian and German Physiological Societies, Copenhagen
    Acta Physiologica, Vol. 198, Suppl. 677, March 2010

  13. Pientka, F.K., Hartmann, E., Köhler, M., Depping, R.
    Human HIF-a hydroxylase PHD2: Topogenesis and effects on HIF-1a transcriptional activity.
    89th Annual Meeting Congress of the DPG 2010, Joint Meeting of the Scandinavian and German Physiological Societies, Copenhagen
    Acta Physiologica, Vol. 198, Suppl. 677, March 2010

  14. Pientka, F.K., Steinhoff, A., Hartmann, E., Köhler, M., Depping, R.
    Regulatory mechanisms underlying intracellular localization of prolyl-4-hydroxylases PHD1 and PHD2 and the impact on HIF-1a transcriptional activity.
    Keystone Symposia "Hypoxia: Molecular Mechanisms of Oxygen Sensing and Response Pathways" Keystone, Colorado, USA, 19.1.-24.1.2010

  15. Steinhoff, A., Köhler, M., Hartmann, E., Depping, R.
    Zelluläres Sauerstoff-sensing: Importine und Exportine sind Mediatoren der intrazellulären Lokalisation der Prolyl-Hydroxylasen PHD1 und PHD2.
    33. Wissenschaftlicher Kongress der Deutschen Hochdruckliga e.V. DHL; Lübeck; 19.-21.11.2009; Posterpreis

  16. Steinhoff, A., Köhler, M., Hartmann, E., Depping, R.
    Cellular oxygen sensing: Importins and exportins are effectors of intracellular localisation of proly-4-Hydroxylases PHD1 and PHD2.
    Kongress für Nephrologie, 1. Jahrestagung der Deutschen Gesellschaft für Nephrologie, Göttingen, 26.09.-29.09.2009

  17. Pientka, F., Steinhoff, A., Hartmann, E., Köhler, M., Depping, R.
    Mediators of protein topogenesis of Hypoxia Inducible Factors (HIF) and Prolyl-Hydroxylases (PHD) 
    8th International Luebeck Conference on the "Pathophysiology and Pharmacology of Erythropoietin and other     Hemopoietic Growth Factors, Lübeck, 30.07-01.08.09
    American Journal of Hematology, Vol. 84, Issue9, 2009

  18. Heidbreder, M., Jöhren, O., Depping, R., Dominiak, P., Dendorfer, A.
    Identification of Eight HIF-3α Splice Variants.
    8th International Luebeck Conference on the "Pathophysiology and Pharmacology of Erythropoietin and other Hemopoietic Growth Factors, Lübeck, 30.07-01.08.09

  19. Lampe, M., Pientka, F.K., Steinhoff, A., Möckel, S., Köhler, M.,
    Depping, R.
    Importin α Mutants - Characterization of Binding Properties to Oxygen-Sensing Proteins.
    8th International Luebeck Conference on the "Pathophysiology and Pharmacology of Erythropoietin and other Hemopoietic Growth Factors, Lübeck, 30.07-01.08.09

  20. Möckel, S., Pientka, F.K., Steinhoff, A., Lampe, M., Köhler, M., Depping, R.
    Importins are mediators of subcellular localization of Prolyl-4-Hydroxylase PHD1.
    8th International Luebeck Conference on the "Pathophysiology and Pharmacology of Erythropoietin and other Hemopoietic Growth Factors, Lübeck, 30.07-01.08.09

  21. Pientka, F.K., Steinhoff, A., Lampe, M., Möckel, S., Köhler, M., Depping, R.
    Mediation of nuclear transport of human HIF-α hydroxylase PHD2 by untypical structural motifs.
    8th International Luebeck Conference on the "Pathophysiology and Pharmacology of Erythropoietin and other Hemopoietic Growth Factors, Lübeck, 30.07-01.08.09

  22. Ströfer, M., Dunst, J., Jelkmann, W., Depping, R.
    Curcumin impacts on HIFα protein levels.
    8th International Luebeck Conference on the "Pathophysiology and Pharmacology of Erythropoietin and other Hemopoietic Growth Factors, Lübeck, 30.07-01.08.09

  23. Renner, A., Ströfer, M., Depping, R., Jelkmann, W., Dunst, J., Metzen, E.
    Hypoxia in radiooncology.
    8th International Luebeck Conference on the "Pathophysiology and Pharmacology of Erythropoietin and other Hemopoietic Growth Factors, Lübeck, 30.07-01.08.09

  24. Jung, F., Depping, R., Stoelting, S., Hellberg, AK., Sievers, HH., Wagner, KF.
    Stem cell therapy derived CD133+- bone marrow progenitor cells secrete angiogenic, chemotactic, and inflammatory cytokines.
    3rd Annual Congress of the German Society for Stem Cell Research / Congress on Regenerative Biology and Medicine, Stuttgart, 09.10.-11.10.2008

  25. Steinhoff, A., Kaiser, FJ., Depping, R.
    Sumoylation of HIF-1α and HIF-2α.
    33rd FEBS Congress & 11th IUBMB Conference, Athens, 28.06.-03.07.2008
    FEBS Journal, Vol. 275, Suppl. 1, Jun. 2008

  26. Will, C., Albrecht, M., Gkalympoudis, S., Depping, R.,
    Gillessen-Kaesbach, G., Lüdecke, H., Kaiser, FJ.
    The transcription factor TRPS1 interacts with the RINGfinger ubiquitin ligase ARKADIA.
    European Human Genetics Conference 2008, Barcelona, 31.05.-03.06.2008
    European Journal of Human Genetics, Vol. 16, Suppl 2, May 2008

  27. Hilz, A., Schillinger, T., Schindler, S.G., Köhler, M., Depping, R.
    Characterisation of NLS in human PHD1 and PHD3.
    32nd FEBS Congress Molecular Machines, Wien, 07.07.-12.07.2007
    FEBS Journal, Vol. 274, Suppl. 1, Jul. 2007

  28. Hilz, A., Schindler, SG., Köhler, M., Depping, R.
    Nuclear Import of human HIF-1a hydroxylases: Characterisation of NLS in human PHD1 and PHD3.
    86th Annual Meeting Congress of the DPG 2007
    Acta Physiologica, Vol. 189, Suppl. 653, March 2007

  29. Heidbreder, M., Jöhren, O., Depping, R., Dominiak, P., Dendorfer, A.
    Identifizierung von acht HIF-3α Spleißvarianten.
    48. Frühjahrstagung der DGPT 2007, Mainz, 13.03.-15.03.2007

  30. Depping, R., Schindler, S., Kettelhake, A., Hilz, A., Köhler, M., Metzen, E.
    The intracellular distribution of human oxygen sensing HIF-a hydroxylases PHD1, PHD2 and PHD3.
    10th Anniversary STS Meeting “Signal Transduction: Receptors, Mediators and Genes 2006”; Weimar, 02.11.-04.11.2006

  31. Wagner, KF, Jung, F, Depping, R., Stoelting, S, Marxsen, J, Butzal, M, Klein, HM., Schmucker, P., Sievers, HH.
    Autologous endothelial progenitor cells for intraoperative injection in cardiac surgery patients with ischemic heart disease.
    1. Kongress der Deutschen Gesellschaft für Stammzellforschung, Köln, 03.11.-04.11.2006

  32. Hilz, A., Kettelhake, A., Köhler, M., Metzen, E., Depping, R.
    Intracellular Allocation of human HIF-alpha hydroxylases.
    7. Int. Lübeck Conference on the Pathophysiology and Pharmacology of Erythropoietin and other Hemopoietic Growth Factors, Lübeck, 07.09.-09.09.2006 
    Annals of Hematology, Vol 85, Number 9, Sept 2006

  33. Wagner, KF, Sievers, HH., Depping, R.
    Erythropoitin receptor: expression in the human heart and upregulation after cardio-pulmonary bypass: role of hypoxia and possible mechanism of myocardial protection.
    7. Int. Lübeck Conference on the Pathophysiology and Pharmacology of Erythropoietin and other Hemopoietic Growth Factors, Lübeck, 07.09.-09.09.2006

  34. Heidbreder, M., Jansen, T., Dendorfer, A., Jöhren, O., Depping, R.,
    Wagner, KF., Dominiak, P 
    Expression Hypoxie-induzierbarer Faktoren in adipösen und adipösen diabetischen Ratten.
    47. Frühjahrstagung der DGPT, Mainz, 04.04.-06.04.2006, 4.4.-6.4.2006

  35. Depping, R., Schindler, S., Friedrich, B., Metzen, E., Hartmann, E., Köhler, M.
    Characterisation of Importin a  - HIF-1a interaction by mapping of the nuclear localisation sequence.
    85th Annual Meeting Congress of the DPG 2006
    Acta Physiologica, Vol. 186, Suppl. 1, March 2006

  36. Wagner, KF., Marxen, J., Stoelting, S., Jung, F., Hellberg, A., Dourvos, O., Gellissen, R., Depping, R., Schmucker, P., Sievers, HH.
    Mycardial revascularization and stem cell injection in patients with ischemic heart disease.
    85th Annual Meeting Congress of the DPG 2006
    Acta Physiologica, Vol. 186, Suppl. 1, March 2006

  37. Depping, R., Kawakami, K., Hartmut, O., Wagner, JM., Heringlake, M., Sievers, HH., Wagner, KF.
    The erythropoietin receptor is expressed in the human heart and upregulated after cardio-pulmonary bypass: possible mechanism of mayocardial protection.
    35. Jahrestagung der deutschen Gesellschaft für Thorax-, Herz-, und Gefäßchirurgie, Hamburg, 19.-22.02.2006

  38. Köhler, M., Schindler, S., Friedrich, B., Sommer, N., Jelkmann, W., Metzen, E., Kunzendorf, U., Hartmann, E., Depping, R.
    Nuclear Translocation of HIF-1a: Analysis of Importin alpha/beta binding.
    ASN Annual Renal Week Meeting 2005, Philadelphia, 8.-13.11.2005

  39. Wagner, KF., Kawakami, K., Ocker, H., Sievers, HH., Depping, R.
    The erythropoietin receptor is expressed in the human heart and upregulated after cardio-pulmonary bypass: role of hypoxia and possible mechanism of myocardial protection.
    ASA Annual Meeting 2005, Atlanta, 22.10.-26.10.2005

  40. Wagner, KF., Hempel, A., Depping, R., Li, D., Sommer, N.
    Regulation of the cellular expression of the new lung-specific Hypoxia-Induced Mitogenic Factor (HIMF).
    ASA Annual Meeting 2005, Atlanta, 22.10.-26.10.2005

  41. Köhler, M., Schindler, S., Friedrich, B., Sommer, N., Jelkmann, W., Metzen, E., Hartmann, E., Depping, R.
    Nuclear Translocation of HIF-1α - Analysis of Importin alpha/beta binding.
    Kongress für Nephrologie, Saarbrücken, 17.09.-20.09.2005

  42. Depping, R., Schindler, S., Friedrich, B., Sommer, N., Hartmann, E., Jelkmann, W., Metzen, E., Köhler, M.
    Nuclear translocation of hypoxia-sensing transcription factors: involvement of the importin alpha/beta-system.
    30th FEBS Congress and 9th IUBMB, Budapest, 02.07.-07.07.2005
    FEBS Journal, Vol. 272, Suppl. 1, Jul. 2005

  43. Heidbreder, M., Qadri, F., Jöhren, O., Dendorfer, R., Depping, R., Wagner, KF., Dominiak, P.
    Non-hypoxic induction of hypoxia-inducible factors by insulin and 2-deoxy-D-glucose.
    30th FEBS Congress and 9th IUBMB, Budapest, 02.07.-07.07.2005
    FEBS Journal, Vol. 272, Suppl. 1, Jul. 2005

  44. Depping R., Kawakami K., Ocker H., Wagner J., Heringlake M., Noetzold, A., Sievers HH., Wagner KF.
    The erythropoietin receptor is expressed in the human heart and upregulated after cardio/pulmonary bypass: role of hypoxia and possible mechanism of mycardial protection.
    Euroanesthesia 2005, Wien, 28.05.-31.05.2005

  45. Günther A., Lohse I., Depping R., Sommer N., Hempel A., Löh B., Klein J., Hartmann E., Li D., Wagner KF.
    Regulation of the cellular expression of the new lung-specific protein Hypoxia-Induced Mitogenic Factor (HIMF).
    Euroanesthesia 2005, Wien, 28.05.-31.05.2005

  46. Heidbreder, M., Qadri, F., Dendorfer, A., Depping, R., Jöhren, O., Wagner, KF., Dominiak, P.
    Nicht-hypoxische transkriptionelle Induktion von HIF-3a durch Hypoglykämie und Glukoprivation.
    71. Jahrestagung der deutschen Gesellschaft für Kardiologie, Mannheim,31.3.-2.4.2005
    Z. Kardiol 94: Suppl.1 2005

  47. Dendorfer A., Heidbreder M., Qadri F., Jöhren O., Depping R., Wagner K, Fröhlich F., Dominiak P. 
    Hypoxie-unabhängige transkriptionelle Induktion von HIF-3α durch Insulin und 2-Deoxyglukose.
    46. Frühjahrstagung der DGPT 2005, Mainz, 15.03.-17.03.2005

  48. Depping, R., Schindler, S., Friedrich, B., Sommer, N., Jelkmann, W., Hartmann, E., Köhler, M., Metzen,E.
    Nuclear translocation of HIF-1a: Analysis of importin alpha/beta binding.
    84th Annual Meeting Congress of the DPG 2005
    European Journal of Physiology, Vol. 449, Suppl. 1, Mar. 2005

  49. Günther,A., Lohse,I., Depping,R., Sommer,N., Hempel,A., Löh,B.,Klein,J., Hartmann,E., Li,D., Wagner,KF
    Regulation of the cellular expression of Hypoxia-induced Mitogenic Factor.
    84th Annual Meeting Congress of the DPG 2005
    European Journal of Physiology, Vol. 449, Suppl. 1, Mar. 2005

  50. Wagner, KF., Depping, R., Dodd-O, J., Roger, JA., Dechun, L.
    HIMF has Anti-Apoptotic Action and is Upregulated in the Developing Lung: Co-expression with HIF-2α.
    ASA Annual Meeting 2004, Las Vegas, 22.10.-26.10.2004

  51. Wagner, KF., Hasegawa, J., Shibata, J., Depping, R., Uhlig, S.
    Pulmonary Vascular Reactivity: New insights from Transgenic Mice with Excessive Erythrocytosis.
    ASA Annual Meeting 2004, Las Vegas 22.10.-26.10.2004

  52. Wagner, KF., Hasegawa, J., Shibata, D., Depping, R., Jelkmann, W., Uhlig, S.
    Pulmonary Vascular Reactivity: New Insight from Transgenic Mice with Excessive Erythrocytosis.
    Euroanesthesia 2004: Annual Meeting of the European Society of Anesthesiologists; Lisbon 05.-08.06.2004; Posterpreis

  53. Wagner, KF., Hasegawa, J., Shibata, J., Bahlmann, M., Depping, R., Schmucker, P., Uhlig, S.
    Pulmonales Remodeling: Polyzythämie oder Hypoxie, was zählt mehr?
    Deutscher Anästhesiecongress in Nürnberg, 19.06.-22.06.2004

  54. Depping,R., Tiemann,B., Nivinskas,R., Rüger,W.
    Catalytic properties of the bacteriophage T4 ADP-Ribosyltransferases ModA and ModB.
    Biospektrum Sonderausgabe zur VAAM Jahrestagung 2004, 28-31.03.2004

  55. Depping,R., Shibata,J., Marti,H., Wagner,K.F., Wenger,R.H.,
    Katschinski, D.M.
    A specific HIF-1a isoform in human and mouse testis.
    6. Int. Lübeck Conference on the Pathophysiology and Pharmacology of Erythropoietin and other Hemopoietic Growth Factors, 26.06.-29.06.2003
    Annals of Hematology, Vol 82, Number 6, June 2003

  56. Depping, R., Shibata,J., Marti,H., Wagner,K.F., Wenger,R.H.,
    Katschinski, D.M.
    A novel HIF-1a isoform in human testis.
    82nd Annual Meeting Congress of the DPG, 02.03.-05.03.2005
    European Journal of Physiology, Vol. 445, Suppl. 1, Feb. 2003

  57. Sommer,N., Depping,R., Rüger,W.
    Computer modeling and mutation analysis of the T4 alpha-glycosyltransferase.
    Fall Meeting of the Gesellschaft für Biochemie und Molekularbiologie, Bochum, 9-12.09.2001
    Biol. Chem., 382, special supplement, S169 (2001)

  58. Tiemann,B, Depping,R. & Rüger,W.
    The ADP-ribosyltransferases of bacteriophage T4.
    12TH Evergreen International Phage Biology Meeting, 16.-20. Juli 1998